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ATP Working Paper Series—Working Paper 04-01
Catalyzing the Genomics Revolution: ATP's Tools for DNA Diagnostics Focused Program


APPENDIX A—Intellectual Property from ATP-Funded Projects on DNA Diagnostic Tools

ATP project title (project number)

Performing organization

No. of patents

Genosensor Technology Development (92-01-0044)

Genosensor Consortium (JVL)
Beckman Instruments (JVP)

2
4

Hyperthermophilic Microorganisms in Molecular Biology and Biotechnology (93-01-0113)

United States Biochemical Corporation (SA)

8

Standardization of 2-D Protein Analysis Using Manufacturable Gel Media (94-01-0284)

Large Scale Proteomics Corporation (SA)

4

Molecular Recognition Technology for Precise Design of Protein-Specific Drugs (94-01-0404)

CuraGen Corporation (JVL)

17*

Compact Blue Laser for Diagnostics (94-05-0004)

Uniphase, Laser Division (JVL)

4

Development of Rapid DNA Medical Diagnostics (94-05-0006)

GeneTrace Systems, Inc. (SA)

9

Development of a Generic Technology for the Targeted Detection and Cleavage of DNA and RNA (94-05-0012)

Third Wave Technologies, Inc. (SA)

10

Miniature Integrated Nucleic Acid Diagnostic (MIND TM ) Development (94-05-0016)

Affymetrix (JVL)
Molecular Dynamics, Inc. (JVP)

1
2

Molecular Cytogenetics Using the GeneScope: An Ultrafast, ulticolor System for Automated FISH Analysis (94-05-0017)

Bio-Rad Laboratories (SA)

1

SBH Format 3 Megabase Diagnostics Instrumentation (94-05-0018)

Hyseq, Inc. (SA)

6

DNA Diagnostic Systems Based on Novel Chem-jet Techniques (94-05-0019)

Incyte Pharmaceuticals, Inc. (SA)

5

Development and Commercial Application of Genosensor Based Comparative Genome Hybridization (94-05-0021)

Vysis, Inc. (SA)

4

Integrated Microfabricated DNA Analysis Device for Diagnosis of Complex Genetic Disorders (94-05-0027)

CuraGen Corporation (JVL)

7

MicroLab: A High-Throughput, Low-Cost Approach to DNA Diagnostics by Array Hybridization (94-05-0029)

Sarnoff Corporation (SA) 41

41

Diagnostic Laser Desorption Mass Spectrometry Detection of Multiplex Electrophore Tagged DNA (94-05-0030)

Bruker Analytical Systems, Inc. (JVL)

7

Automated DNA Amplification and Fragment Fragment Size Analysis (94-05-0033)

Qualicon (formerly DuPont, FQMS Group) (SA)

1

RNA Binding Protein Technology for Identification of Novel Therapeutics (95-01-0098)

Message Pharmaceuticals, Inc. (SA)

3

Real-Time Micro-PCR Analysis System (95-08-0006)

PE Corporation (formerly Applied
BioSystems) (JVL)
3M (JVP)

2
2

An Integrated Microelectronic DNA Diagnostic System (95-08-0009)

Nanogen, Inc. (SA)

3

Development of Bar Code Diagnostics for DNA Diagnostics (95-08-0012)

Vysis, Inc. (SA)

3

Self-Contained Cartridge Integrating Nucleic Acid Extraction, Specific Target Amplification, and"Dip Stick" Immediate Detection (95-08-0015) Molecular Innovations (SA) 3
Generation and Development of Novel Nucleic Acid Binding Proteins and Their Use as DNA
Diagnostics (95-08-0016)
Sangamo BioSciences, Inc. (SA) 2
DNA Diagnostics Using Self-Detected Target- Cycling Reaction (SD-TCR) (95-08-0017) NAVIX, Inc. (SA) 1
Programmable Nanoscale Engines for Molecular Separation (96-01-0141) CuraGen Corporation (SA) 3
A Portable Genetic Analysis System (96-01-0172) Nanogen, Inc. (SA) 7
Simple, Generic, and Low-Cost Genetic-Based Tools for Disease Detection, Monitoring, and Intervention (97-01-0135) Third Wave Technologies, Inc. (SA) 4
DNA Diagnostics for the Point of Care Using Clinical Electronic Nucleic Acid Detection (98-08-0003) Micro Sensors, Inc. (SA) 1
Multiplex DNA Diagnostic Assay Based on Microtransponders (98-08-0020) PharmaSeq, Inc. (SA) 2
Multiplexed Sample Preparation Microsystem ACLARA for DNA Diagnostics (98-08-0029) Biosciences, Inc. (SA) 3
Integrated, Micro-Sample Preparation System for Genetic Analysis (98-08-0031) 3M (JVP) 7
Grand total 179

Legend: SA - single applicant; JVL - joint venture lead; JVP - joint venture participant.
*Two copyrights were realized from this project as well as the 17 patents.

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Date created: August 1, 2005
Last updated: August 5, 2005

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